medical emergency

  • people with TIA at high risk of early stroke

    • 12% @ 7d

    • 20% @ 90d

    • 1/2 will occur wihtin first 48hrs after TIA

    • 85% of strokes that follow TIA will be fatal or disabling

  • diagnosis more likely to be correct:

    • sudden onset of symptoms

      • maximal neurological deficit at onset

      • symptoms typical of focal loss of brain function

        • unilateral weakness

        • speech disturbance

      • rapid recovery of symptoms

        • 30-60min

        • if any residual symptoms

          • manage for stroke compared to TIA

Immediate assessment and intervention

reduce the risk of stroke after TIA

  • Aspirin

    • 300mg stat if aspriin naive anad 75-150mg daily
  • Risk assessment

    • ABCD2

      • Age >60 (1)

      • BP ≥ 140/90 (1)

      • Clinical features

        • unilateral weakness (2)

        • speech impairment without weakness (1)

      • duration of symptoms

        • ≥ 60mins (2)

        • 10-59min (1)

      • diabetes (on medication) 1

    • Risk of stroke:

      • 0-3

        • 2d 1%

        • 7d 1.2%

        • 90d 3.1%

      • 4-5

        • 2d 4.1%

        • 7d 5.9%

        • 90d 9.8%

      • 6-7

        • 2d 8.1%

        • 7d 11.7%

        • 90d 17.8%

    • high risk:

      • ABCD2 score ≥ 4

      • cresencdo TIA

      • AF

      • taking OAC

      • require urgent assessment - def. within 24hrs

    • low risk

      • ABCD2 \< 4

      • more than 1 week after TIA symptoms

      • require specialist assessment and investigations within 7d

    • if treating dr confident of diagnosis; has ready acecss to brain and carotid imaging anad can initiate treatment

      • specialist review may not be required

Immediate secondary prevention measures

  • assess risk factors

  • antiplatelet

    • aspirin

    • aspirin + dipyridamole

    • clopidogrel

  • BP lowering

  • statin

  • OAC

  • nicotine replacement

initiate at first point of health care i.e. immediately

do not need to wait for brain imaging (except OAC)

fully recovered = intracerebral haemorrhage risk very low

Follow-up

  • 1 month

Early assessment and diagnosis

  • investigations

    • FBC

    • electrolytes

    • ESR

    • renal function

    • lipid

    • HbA1c

    • ECG